An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity
نویسندگان
چکیده
منابع مشابه
Incident open-angle glaucoma and intraocular pressure.
PURPOSE To evaluate the role of baseline intraocular pressure (b-IOP) as a risk factor for incident open-angle glaucoma (OAG) in participants of African origin from the Barbados Eye Studies. DESIGN Population-based 9-year cohort study. PARTICIPANTS Three thousand two hundred twenty-two persons examined during the study period who were free of glaucoma at baseline and at risk of developing O...
متن کاملprimary open-angle glaucoma risk factors
purpose: the objective of this study was to identify possible risk factors associated with primary open-angle glaucoma (poag). methods: a case-control study included patients seen at rasoul-akram hospital ophthalmology clinic. cases were consecutive patients with confirmed unilateral or bilateral poag presented during the study period. controls were a random sample of all other patients aged 30...
متن کاملPrimary Open-Angle Glaucoma Risk Factors
Purpose: The objective of this study was to identify possible risk factors associated with primary open-angle glaucoma (POAG). Methods: A case-control study included patients seen at Rasoul-Akram Hospital ophthalmology clinic. Cases were consecutive patients with confirmed unilateral or bilateral POAG presented during the study period. Controls were a random sample of all other patients aged 30...
متن کاملDiurnal blood pressure parameters in normal tension glaucoma, primary open angle glaucoma, and healthy subjects
OBJECTIVE The pathophysiology of glaucoma is still undisclosed. Cardiovascular hemodynamic changes are hypothesized to contribute to glaucoma. This study aimed to determine the differences in the diurnal blood pressure (BP) of patients with normal tension glaucoma (NTG), primary open angle glaucoma (POAG), and controls without glaucoma. METHODS A total of 129 patients were included in this st...
متن کاملFamily score as an indicator of genetic risk of primary open-angle glaucoma.
OBJECTIVES To assess the genetic risk of open-angle glaucoma (OAG) in individuals by calculating a family score (FS), which summarizes the information of all relatives including their disease status, age, sex, and degree of kinship and to examine the genetic contribution to OAG with and without an increased intraocular pressure. METHODS Case and control probands, derived from the Rotterdam St...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Ophthalmology
سال: 2020
ISSN: 0161-6420
DOI: 10.1016/j.ophtha.2019.12.025